About the Howard P. House, MD Memorial Lecture for Advances in Otology
Howard P. House, MD’s passion for sharing knowledge through research and education is the reason we honor him through the establishment of a lectureship and to ensure that Dr. House’s desire to share knowledge on a global plane continues.
2025 Lecturer
Lawrence R. Lustig, MD
Saturday, October 11, at 4:00 pm
Cochlear Gene Therapy for Genetic Deafness
Lawrence R. Lustig, MD is an otolaryngologist who specializes in otology, neurotology, and skull base surgery. Dr. Lustig grew up in Northern California and completed his undergraduate studies at the University of California, Berkeley. He graduated from the University of California, San Francisco (UCSF) School of Medicine, where he also completed his otolaryngology residency. After residency, Dr. Lustig completed his neurotology and skull base surgery fellowship at Johns Hopkins University and remained on staff at Johns Hopkins through 2004.
In 2004, he was recruited back to UCSF to lead the Division of Otology and Neurotology in the Otolaryngology Department. In 2014, he accepted positions at Columbia University and New York Presbyterian Hospital where he practices today as the Howard W. Smith Professor and chair of the Department of Otolaryngology.
Dr. Lustig’s interdisciplinary research has helped pioneer cochlear gene therapy for genetic forms of hearing loss. He is also one of the lead investigators for the otoferlin gene therapy trial sponsored by Regeneron. Prior work in his lab has included studies on cochlear bone development and how the material properties of bone enclosing the inner ear contribute to hearing. He is considered one of the foremost authorities on cochlear implants in the United States.
Dr. Lustig has published more than 125 articles in peer-reviewed journals, as well as numerous book chapters. He has co-edited several textbooks, including Clinical Neurotology: Diagnosing and Managing Disorders of Hearing, Balance, and the Facial Nerve and Disorders of the Vestibular System. He currently serves as editor-in-chief of Otology & Neurotology, the foremost medical journal in the subspeciality.
About the Lecture
The Howard P. House, MD Memorial Lectures for Advances in Otolaryngology honors Dr. House’s passion for sharing knowledge through research and education. The lecture was established to ensure that Dr. House’s desire to share knowledge on a global plane continues.
Learning Objectives:
- Understand how genes are delivered to the cochlea to treat genetic deafness.
- Understand some of the mouse models that are under study for genetic deafness.
- Receive an update on the clinical trial results for otoferlin-related deafness in humans.
- Understand the future landscape for treating genetic deafness.
Previous Lecturers:
- 2023: Nancy M. Young, MD
- 2021: Lloyd B. Minor, MD
- 2019: Andrea Vambutas, MD
- 2017: Herbert Silverstein, MD, FACS
- 2015: Konstantina M. Stankovic, MD, PhD
- 2013: Derald E. Brackmann, MD
- 2011: Professor Vittorio Colletti
- 2010: Rodney C. Perkins, MD
- 2009: Michael E. Glasscock III, MD
- 2008: John W. House, MD, on behalf of William F. House, DDS, MD
