High Priority Status: No / N/A
CBE Number: N/A
Measure Description:
Percentage of patients aged 18 years and older diagnosed with a neck mass and suspected/increased risk of malignancy who had a fine needle aspiration (FNA), or refer the patient to someone who can perform FNA and receive a neck computed tomography (or magnetic resonance imaging) with contrast.
Instructions:
This measure is to be submitted a minimum of once per performance period for patients with a new neck mass. This measure may be submitted by clinicians based on the services provided and the measure-specific denominator coding. This measure has two strata separated by numerical indicators (i.e., denominator exception 2 is evaluated in the instance numerator 2 is not performed).
Denominator:
- Patients aged 18 years and older diagnosed with a neck mass and *suspected/increased risk of malignancy
- Patients aged 18 years and older diagnosed with a neck mass and *suspected/increased risk of malignancy
Denominator Note:
- Patients with a new neck mass who are at increased risk for malignancy because the patient lacks a history of infectious etiology, and the mass has been present for ≥ 2 weeks without significant fluctuation or the mass is of uncertain duration.
- A new neck mass is defined as a neck mass diagnosis for the first time in life
- Patients with a neck mass who are at increased risk for malignancy based on ≥ 1 of these physical examination characteristics: fixation to adjacent tissues, firm consistency, size > 5 cm, or ulceration of overlying skin.
- Patients with a neck mass who are at low risk for malignancy based on ≥ 1 of these physical examination characteristics: mobile, fluctuant, size ≤ 1.5cm, or swollen lymph nodes.
Denominator Exclusions:
- None
- None
Denominator Criteria:
Patients aged 18 years and older
AND
Diagnosis: Neck Mass
AND
Suspected/Increased Risk of Malignancy Criteria (Reference: Denominator Note)
AND
Patient Visit: Encounter Visit
For a list of codes that qualify as denominator eligible visits, reference Addendum attached.
Numerator:
- Patients that have a FNA, or refer the patient to someone who can perform an FNA.
- Patients that received a neck computed tomography scan or magnetic resonance imaging with contrast
- Total patient performance average on the above two components
Note: This measure assesses the completion of an FNA prior to an open biopsy, if further testing is required.
Denominator Exceptions:
- Documentation of a system reason for not completing an FNA (i.e., cytopathologist unavailable to read FNA)
- FNA results negative for malignancy.
- Medical reason(s) to not do an FNA (contraindication, risk, competing diagnosis, etc.)
Measure Classifications:
- Submission Pathway: Traditional MIPS
- Measure Type: Process
- High Priority Type: Patient Safety
- Meaningful Measures Area: Appropriate Use of Healthcare
- Care Setting(s): Ambulatory Care: Clinician Office/Clinic
- Includes Telehealth: No
- Number of Performance Rates: 1
- Inverse measure: No
- Continuous measure: No
- Proportional measure: Yes
- Ratio measure: No
- Risk Adjusted measure: No
Clinical Recommendation Statement:
Fine-needle aspiration (FNA), rather than open biopsy, is the preferred method for cancer diagnosis in a neck mass. Open biopsy is suboptimal because it risks tumor seeding and local and regional tumor recurrence.
Clinicians should identify patients with a neck mass who are at increased risk for malignancy when the patient lacks a history of infectious etiology and the mass has been present for =2 weeks without significant fluctuation or the mass is of uncertain duration.
Clinicians should identify patients with a neck mass who are at increased risk or malignancy based on =1 of these physical examination characteristics: fixation to adjacent tissues, firm consistency, size >1.5 cm, and/or ulceration of overlying skin. Both CT and MRI are effective tools in the assessment of neck masses, although CT has several benefits that support its utilization as a primary imaging modality.91 CT is more read-ily available, costs considerably less, and is generally more easily tolerated by patients because of shorter scanning time (<5 minutes) and larger scanner bore. While CT utilizes ion-izing radiation, the average dose of 3 mSv (equivalent to approximately 150 chest x-rays) is considered acceptable in the adult population.92 MRI offers improved tissue contrast and can help detect subclinical tumors not evident with nasal endoscopy.93 MRI is preferred when a primary tumor of the nasopharynx is suspected or when there is cranial nerve abnor-mality on physical examination because of its improved sensi-tivity to abnormalities of the skull base and in the detection of perineural spread.
Although the natural history of HPV-OPC is not well understood, this case series suggests that it can be slow growing and mimic benign processes, leading to diagnostic delays. Adults presenting with neck masses should undergo complete diagnostic evaluation.
Base of Tongue/Tonsil/Posterior Pharyngeal Wall/Soft Palate Workup:
- Tumor human papillomavirus (HPV) testing by p16 immunohistochemistry (IHC) required
- H&P including a complete head and neck exam; mirror and fiberoptic examination as clinically indicated
- Biopsy of primary site or fine-needle aspiration (FNA) of the neck
- CT with contrast and/or MRI with contrast of primary and neck
- As clinically indicated: EUA with endoscopy Preanesthesia studiesFDG-PET/CTeChest CTe (with or without contrast)Dental evaluating including PanorexNutrition, speech and swallowing evaluation/therapy, and audiogramSmoking cessation counselingFertility/reproductive counseling
- Multidisciplinary consultation as clinically indicated
Davis, R.J., Rettig, E., Aygun, N., Rooper, L., D’Souza, G., Eisele, D.W. and Fakhry, C. (2020), From presumed benign neck masses to delayed recognition of human papillomavirus–positive oropharyngeal cancer. The Laryngoscope, 130: 392-397. https://doi.org/10.1002/lary.27946Pynnonen, M.A., Gillespie, M.B., Roman, B., Rosenfeld, R.M., Tunkel, D.E., Bontempo, L., Brook, I., Chick, D.A., Colandrea, M., Finestone, S.A., Fowler, J.C., Griffith, C.C., Henson, Z., Levine, C., Mehta, V., Salama, A., Scharpf, J., Shatzkes, D.R., Stern, W.B., Youngerman, J.S. and Corrigan, M.D. (2017), Clinical Practice Guideline: Evaluation of the Neck Mass in Adults. Otolaryngology–Head and Neck Surgery, 157: S1-S30. https://doi.org/10.1177/0194599817722550
National Comprehensive Cancer Network. Bone Cancer (Version 2.2023). https://www.nccn.org/professionals/physician_gls/pdf/head-and-neck.pdf. Accessed August 22, 2023.
Rationale:
Neck masses are common in adults, but often the underlying etiology is not easily identifiable. While infections cause most of the neck masses in children, most persistent neck masses in adults are neoplasms. Malignant neoplasms far exceed any other etiology of adult neck mass.
Pynnonen, M.A., Gillespie, M.B., Roman, B., Rosenfeld, R.M., Tunkel, D.E., Bontempo, L., Brook, I., Chick, D.A., Colandrea, M., Finestone, S.A., Fowler, J.C., Griffith, C.C., Henson, Z., Levine, C., Mehta, V., Salama, A., Scharpf, J., Shatzkes, D.R., Stern, W.B., Youngerman, J.S. and Corrigan, M.D. (2017), Clinical Practice Guideline: Evaluation of the Neck Mass in Adults. Otolaryngology–Head and Neck Surgery, 157: S1-S30. https://doi.org/10.1177/0194599817722550
Supporting Clinical Practice Guideline (CPG):
For more details, referece the Clinical Practice Guideline: Evaluation of the Neck Mass in Adults (2017)
© 2026 American Academy of Otolaryngology–Head and Neck Surgery Foundation. All rights reserved.
Limited proprietary coding is contained in the measure specifications for convenience. Users of the proprietary code sets should obtain all necessary licenses from the owners of these code sets. The measures, while copyrighted, can be reproduced and distributed, without modification, for noncommercial purposes, e.g. use by health care providers in connection with their practices. Commercial use is defined as the sale, license, or distribution of the measures for commercial gain, or incorporation of the measures into a product or service that is sold, licensed or distributed for commercial gain. Commercial uses of the measures require a license agreement between the user and the American Academy of Otolaryngology – Head and Neck Surgery Foundation.
The measure is not a clinical guideline, does not establish a standard of medical care, and has not been tested for all potential applications. The measure and specifications are provided “as is” without warranty of any kind. Neither the American Academy of Otolaryngology – Head and Neck Surgery Foundation (AAO-HNSF), nor its members shall be responsible for any use of the measure. The AAO-HNSF and its members disclaim all liability for use or accuracy of any Current Procedural Terminology (CPT®) or other coding contained in the specifications.
Addendum
Encounter Visit |
|||
| Measure Element | Code Type | Code | Code Description |
| Denominator – Consultations | CPT | 99241 | Office consultation |
| Denominator – Consultations | CPT | 99242 | Office or other outpatient consultation |
| Denominator – Consultations | CPT | 99243 | Office or other outpatient consultation |
| Denominator – Consultations | CPT | 99244 | Office or other outpatient consultation |
| Denominator – Consultations | CPT | 99245 | Office or other outpatient consultation |
| Denominator – Consultations_telehealth modifier | CPT | 99242 | Office or other outpatient consultation |
| Denominator – Consultations_telehealth modifier | CPT | 99242 | Office or other outpatient consultation |
| Denominator – Consultations_telehealth modifier | CPT | 99242 | Office or other outpatient consultation |
| Denominator – Consultations_telehealth modifier | CPT | 99243 | Office or other outpatient consultation |
| Denominator – Consultations_telehealth modifier | CPT | 99243 | Office or other outpatient consultation |
| Denominator – Consultations_telehealth modifier | CPT | 99243 | Office or other outpatient consultation |
| Denominator – Consultations_telehealth modifier | CPT | 99244 | Office or other outpatient consultation |
| Denominator – Consultations_telehealth modifier | CPT | 99244 | Office or other outpatient consultation |
| Denominator – Consultations_telehealth modifier | CPT | 99244 | Office or other outpatient consultation |
| Denominator – Consultations_telehealth modifier | CPT | 99245 | Office or other outpatient consultation |
| Denominator – Consultations_telehealth modifier | CPT | 99245 | Office or other outpatient consultation |
| Denominator – Consultations_telehealth modifier | CPT | 99245 | Office or other outpatient consultation |
| Denominator – Office Visit | CPT | 99202 | Office or other outpatient consultation |
| Denominator – Office Visit | CPT | 99203 | Office or other outpatient consultation |
| Denominator – Office Visit | CPT | 99204 | Office or other outpatient consultation |
| Denominator – Office Visit | CPT | 99205 | Office or other outpatient consultation |
| Denominator – Office Visit | CPT | 99211 | Office or other outpatient consultation |
| Denominator – Office Visit | CPT | 99212 | Office or other outpatient consultation |
| Denominator – Office Visit | CPT | 99213 | Office or other outpatient consultation |
| Denominator – Office Visit | CPT | 99214 | Office or other outpatient consultation |
| Denominator – Office Visit | CPT | 99215 | Office or other outpatient consultation |
| Denominator – Office Visit_Telehealth Modifier | CPT | 99202 | Office or other outpatient consultation |
| Denominator – Office Visit_Telehealth Modifier | CPT | 99202 | Office or other outpatient consultation |
| Denominator – Office Visit_Telehealth Modifier | CPT | 99202 | Office or other outpatient consultation |
| Denominator – Office Visit_Telehealth Modifier | CPT | 99203 | Office or other outpatient consultation |
| Denominator – Office Visit_Telehealth Modifier | CPT | 99203 | Office or other outpatient consultation |
| Denominator – Office Visit_Telehealth Modifier | CPT | 99203 | Office or other outpatient consultation |
| Denominator – Office Visit_Telehealth Modifier | CPT | 99204 | Office or other outpatient consultation |
| Denominator – Office Visit_Telehealth Modifier | CPT | 99204 | Office or other outpatient consultation |
| Denominator – Office Visit_Telehealth Modifier | CPT | 99204 | Office or other outpatient consultation |
| Denominator – Office Visit_Telehealth Modifier | CPT | 99205 | Office or other outpatient consultation |
| Denominator – Office Visit_Telehealth Modifier | CPT | 99205 | Office or other outpatient consultation |
| Denominator – Office Visit_Telehealth Modifier | CPT | 99205 | Office or other outpatient consultation |
| Denominator – Office Visit_Telehealth Modifier | CPT | 99211 | Office or other outpatient consultation |
| Denominator – Office Visit_Telehealth Modifier | CPT | 99211 | Office or other outpatient consultation |
| Denominator – Office Visit_Telehealth Modifier | CPT | 99212 | Office or other outpatient consultation |
| Denominator – Office Visit_Telehealth Modifier | CPT | 99212 | Office or other outpatient consultation |
| Denominator – Office Visit_Telehealth Modifier | CPT | 99212 | Office or other outpatient consultation |
| Denominator – Office Visit_Telehealth Modifier | CPT | 99213 | Office or other outpatient consultation |
| Denominator – Office Visit_Telehealth Modifier | CPT | 99213 | Office or other outpatient consultation |
| Denominator – Office Visit_Telehealth Modifier | CPT | 99213 | Office or other outpatient consultation |
| Denominator – Office Visit_Telehealth Modifier | CPT | 99214 | Office or other outpatient consultation |
| Denominator – Office Visit_Telehealth Modifier | CPT | 99214 | Office or other outpatient consultation |
| Denominator – Office Visit_Telehealth Modifier | CPT | 99214 | Office or other outpatient consultation |
| Denominator – Office Visit_Telehealth Modifier | CPT | 99215 | Office or other outpatient consultation |
| Denominator – Office Visit_Telehealth Modifier | CPT | 99215 | Office or other outpatient consultation |
| Denominator – Office Visit_Telehealth Modifier | CPT | 99215 | Office or other outpatient consultation |
| Denominator – Office Visit_Telehealth Modifier | CPT | 99211 | Office or other outpatient consultation |
Neck Mass |
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| Denominator – Neck Mass | SNOMEDCT | 10685151000119100 | Mass of skin of neck (finding) |
| Denominator – Neck Mass | SNOMEDCT | 10685151000119100 | Mass of skin of neck |
| Denominator – Neck Mass | SNOMEDCT | 141808001 | Mass of neck |
| Denominator – Neck Mass | SNOMEDCT | 164631007 | Mass of neck |
| Denominator – Neck Mass | SNOMEDCT | 274747003 | Localized swelling, mass and lump, neck (finding) |
| Denominator – Neck Mass | SNOMEDCT | 278004004 | Soft tissue mass of neck |
| Denominator – Neck Mass | SNOMEDCT | 299703001 | Mass of neck (finding) |
| Denominator – Neck Mass | ICD10CM | R22.1 | Localized swelling, mass and lump, neck |