Bilateral Congenital Ossicular Anomalies: Are the Anomalies Symmetric for Both Ears?
Volume169, Issue4Abstract Objective To evaluate whether bilateral congenital ossicular anomalies (COAs) differ regarding ossicular anomalies and hearing loss severities between the ears of the individual. Study Design Retrospective case review. Setting Tertiary referral academic center. Methods Between March 2012 and December 2022, 7 consecutive patients (14…
October 2023
Otorhinologic Disorders in 22q11.2 Deletion Syndrome
Volume169, Issue4Abstract Objective Investigate incidence and natural history of otologic and sinonasal disease associated with 22q11.2 deletion syndrome. Study Design Case series. Setting Tertiary care children's hospital. Methods Charts from consecutive children born 2000 to 2018 with a diagnosis of 22q11.2 deletion, DiGeorge…
October 2023
Associations Between Body Composition and Sensorineural Hearing Loss Among Adults Based on the UK Biobank
Volume169, Issue4Abstract Objective To explore the association between body composition and sensorineural hearing loss (SNHL). Study Design Cross-sectional study, prospective study and Mendelian randomization (MR) analyses. Setting UK Biobank. Methods This cross-sectional study included 147,296 adult participants with complete data on body composition…
October 2023
Health-Related Quality of Life in Children With Unilateral Sensorineural Hearing Loss Following Cochlear Implantation
Volume168, Issue6Abstract Objective Evaluate health-related quality of life (HR-QOL) benefits with cochlear implantation (CI) in children with unilateral sensorineural hearing loss (USNHL) versus bilateral sensorineural hearing loss (BSNHL). Study Design A cross-sectional survey of parents of children who underwent CI for USNHL and…
June 2023
Understanding Barriers to Timely Diagnosis and Intervention Among Immigrant Children With Hearing Loss
Volume169, Issue3Abstract Objective Identify the age at diagnosis and intervention of immigrant and/or non-English-speaking children with hearing loss (HL) and risk factors associated with delays. Identify barriers for non-English-speaking caregivers of deaf/hard-of-hearing children. Study Design Sequential mixed methods…
September 2023
Audiometric and Patient-Reported Outcomes in Single-Sided Deafness Cochlear Implant Recipients Using the CIQOL-35
Volume168, Issue5Abstract Objective Describe the effect that cochlear implantation (CI) has on audiometric outcomes and quality of life (QOL) in patients with single-sided deafness (SSD). Study Design Retrospective case review. Setting Tertiary university hospital system. Methods Preoperative and postoperative AzBio performance and Cochlear Implant Quality…
May 2023
Esophageal Schwannoma Presenting as Neck Mass and Misdiagnosed as Thyroid Nodule: A Case Report
Volume7, Issue1Benign esophageal tumors are rare, occurring at an incidence of <5%.1 Most are asymptomatic and incidentally found by imaging or endoscopy performed for other indications. Because esophageal carcinoma is approximately 50 times more common, the definitive diagnosis of a benign tumor is confirmed by…
January 2023
Vertebral Anomalies in Microtia Patients at a Tertiary Pediatric Care Center
Volume169, Issue2Abstract Objective Microtia is a congenital condition known to be associated with vertebral anomalies and congenital syndromes, most prominently hemifacial microsomia. There is controversy, however, on whether to screen with spinal imaging. Additionally, microtia ear reconstruction utilizes rib harvesting that could potentially worsen pre-existing…
August 2023
Evidence-Based Medicine in Otolaryngology Part 14: Falsehood and Bias
Volume168, Issue6Abstract Objective Falsehood and bias can have tangible effects, whether related to the "hoax" of Corona virus disease/COVID-19 or the impact of personal protective equipment in city-wide news. The spread of false information requires the diversion of time and resources into rebolstering…
June 2023
Systematic Review and Meta-analysis of the Influence of Genetic Variation on Ototoxicity in Platinum-Based Chemotherapy
Volume168, Issue6Abstract Objective The objective of this meta-analysis is to evaluate the impact of genetic polymorphisms on platinum-based chemotherapy (PBC)-induced ototoxicity. Data Sources Systematic searches of PubMed, Embase, Cochrane, and Web of Science were conducted from the inception of the databases to May…
June 2023
Olfaction and Gustation in Children With Primary Ciliary Dyskinesia
Volume7, Issue1Abstract Objective Primary ciliary dyskinesia (PCD) is a rare autosomal recessive disorder whereby abnormal cilia cause a wide array of respiratory tract manifestations including chronic rhinosinusitis. The purpose of this study was to determine whether olfaction and gustation are impaired in children with PCD. Study…
January 2023
Prognostic Significance of a Model Based on Acetaldehyde Dehydrogenase 2 Genetic Polymorphisms in Laryngeal Carcinoma
Volume169, Issue3Abstract Objective Because of the high costs associated with early-stage laryngeal carcinoma diagnosis and prognosis prediction, this study attempts to find valuable targets to establish a novel predictive model by focusing on the aldehyde dehydrogenase 2 (ALDH2) genotype and other peripheral blood markers. Study…
September 2023
Reduced Risk of Corporal Tumors in Patients With Head and Neck Paragangliomas With p.Pro81Leu Mutations
Volume169, Issue3Abstract Objective Patients with head and neck paragangliomas who are positive for the SDHD p.Pro81Leu (P81L) mutation are thought to have a distinct phenotype from other SDHx mutations, but few studies have focused on this mutation. The objective of this study was to determine…
September 2023
Evolving Management of Acute Mastoiditis: Analysis of the Pediatric Health Information System Database
Volume169, Issue2Abstract Objective The optimal management of acute mastoiditis remains controversial. Most existing studies are retrospective single-institutional experiences with small cohorts. Our objectives were to analyze the treatment of acute mastoiditis by pediatric centers across the United States and changes in management over time. Study…
August 2023
Prevalence of Cochlear Nerve Deficiency and Hearing Device Use in Children With Single-Sided Deafness
Volume169, Issue2Abstract Objective This study aimed to assess the prevalence of cochlear nerve deficiency (CND) in a cohort of pediatric patients with single-sided deafness (SSD). A secondary objective was to investigate trends in intervention and hearing device use in these children. Study Design Case series…
August 2023
Auditory Outcomes in Children Who Undergo Cochlear Implantation Before 12 Months of Age: A Systematic Review
Volume169, Issue2Abstract Objective To systematically review the literature to determine auditory outcomes of cochlear implantation in children ≤12 months old. Data Source PubMed, EMBASE, Medline, CINAHL, Cochrane, Scopus, and Web of Science databases were searched from inception to 9/1/2021 using PRISMA guidelines. Review Methods…
August 2023
The Course of Hearing Loss in Patients With a Progressive Vestibular Schwannoma
Volume169, Issue3Abstract Objective This study evaluates the natural course of hearing loss (HL) prior to treatment in patients with progressive tumors and an indication for active intervention. Evaluating this patient group specifically can put hearing outcomes after vestibular schwannoma therapy into an adequate context. Study Design…
September 2023
Abnormal Subjective and Audiometric Auditory Function in Migraine
Volume168, Issue6Abstract Objective To identify if migraine is associated with auditory deficits and if the auditory profile of migraine is distinct from other pain syndromes, such as chronic pain. Study Design Cross-sectional, retrospective. Setting A total of 5273 respondents of the 1999 to 2004 National…
June 2023